Q. What is the diagnosis?( Clue: Xlinked dominant disease)
1) Becker disease
2) Incontinenta Pigmenti
3) Ichthyosis
4) Pemphigus vulgaris
Ans: 2) Incontinenta Pigmenti.
Incontinentia pigmenti is a complex developmental syndrome due to an X-linked dominant
trait that is usually lethal in males; 95% of cases are females.Vesicular, verrucous, and pigmented
skin lesions are usually seen.
Q). 34 years old female after sun exposure, what is the diagnosis?
1) Acne
2) Solar eczema
3) polymorphic light eruption
4) SLE
Ans: 3) Polymorphic light eruption.
This is a common intermittent skin reaction to UV exposure, which may represent a delayed type
hypersensitivity response to UV-induced cutaneous antigens. PLE presents with
an itchy, non-scarring, symmetrical papular rash
on light-exposed sites within hours or days of significant sun exposure in young female usually below 30 years of age.
Large and small papules, papulopustules, and vesicles can occur. The eruption is transient, and resolves within several days, but it may persist if exposure continues.
Cutaneous lupus should be considered as differential diagnosis, and a minority of patients with PLE may subsequently develop lupus after several years .
Q). Skin eruption in a 26 year old male after scarlet fever.what is the diagnosis?
1) TSS
2)SSSS
3) Septic shock
4) Lyells syndrome
Ans: 1) TSS.
Scarlet fever (scarlatina) is an acute infection with a toxin-producing strain of Streptococcus pyogenes. Complications caused by the toxin or bacterial invasion include meningitis,
osteomyelitis, rheumatic fever, and glomerulonephritis.
