CELL MEMBRANE

Q. Several segments of the polypeptide chain of integral membrane proteins usually span the lipid bilayer. These segments frequently
A) Adopt an α-helical configurati on
B) Contain many hydrophilic amino acids
C) Form covalent bonds with cholesterol
D) Contain unusually strong pepti de bonds

ans: A

Membrane-spanning segments of integral proteins frequently adopt an α -helical
conforma on because this structure maximizes the opportuni es for the polar pep de
bonds to form hydrogen bonds with one another in the hydrophobic interior of the lipid
bilayer. These segments are composed largely of amino acids with nonpolar hydrophobic side
chains that interact with the surrounding lipids. There are no covalent bonds with cholesterol or phospholipids, and the pepti de bonds are not unusually strong.



Exp. Adopt an α-helical configura on Ref: Ganong - Review of Medical Physiology 23rd
Ed Page 8,9

PGMEE TEST 1 /2014 ( answers)

                              PGMEE TEST 1 /2014
                 
                      Total number of questions: 20. Maximum score: 80


Single best answer. No negative marks.

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Question ID: 1
cozen test is used in-

Options:
(1)  anterior shoulder instability
(2)  posterior shoulder instability
(3) tennis elbow ( ans) (Score = 4.0)
(4)  golfers elbow

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Question ID: 2
In sarcoidosis cd4/cd8 count ratio is- 

Options:
(1) [  ] >2.5
(2) [ans] >3.5 (Score = 4.0)
(3) [  ] >4.5
(4) [  ] >1.5

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Question ID: 3
1st kidney transplantation was done by-


Options:
(1) [  ] hardy
(2) [  ] starzl
(3) [ans] lawler (Score = 4.0)
(4) [  ] cooley

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Question ID: 4
classification of choledochal cyst was done by


Options:
(1) [  ] alonso-lej
(2) [ans] bismuth strasberg (Score = 4.0)
(3) [  ] kelly patterson
(4) [  ] kuppfer askin

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Question ID: 5
fanconi anaemia is a side effect of-


Options:
(1) [ans] tenofovir (Score = 4.0)
(2) [  ] atazanavir
(3) [  ] abacavir
(4) [  ] abacavir

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Question ID: 6
pink test is used for-


Options:
(1) [ans] milk test (Score = 4.0)
(2) [  ] osmotic fragility
(3) [  ] respiratory quotient
(4) [  ] card test

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Question ID: 7
youssef's syndrome is-


Options:
(1) [  ] VVF
(2) [ans] VUF (Score = 4.0)
(3) [  ] uretero vaginal fistula
(4) [  ] endometriosis

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Question ID: 8
eflornithine is used in-


Options:
(1) [  ] leishmaniasis
(2) [  ] asbestosis
(3) [ans] african trypanosomiasis (Score = 4.0)
(4) [  ] schistosomiasis

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Question ID: 9
pulmonary fibrosis would be expected to produce-


Options:
(1) [  ] histotoxic hypoxia
(2) [  ] decreased vital capacity
(3) [ans] cyanosis (Score = 4.0)
(4) [  ] emphysema

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Question ID: 10
prehn sign is positive in-

Options:
(1) [  ] acute balanoposthitis
(2) [ans] epididymoorchitis (Score = 4.0)
(3) [  ] epididymitis
(4) [  ] torsion of testis

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Question ID: 11
most common organism causing Hospital acquiring infection-


Options:
(1) [  ] staph aureus
(2) [ans] E coli (Score = 4.0)
(3) [  ] coagulase negative staph
(4) [  ] candida

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Question ID: 12
organism causing Carrion disease is-

Options:
(1) [  ] bartonella angiomatosis
(2) [ans] B. bacilliformis (Score = 4.0)
(3) [  ] B. henselae
(4) [  ] none of the above

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Question ID: 13
Ackerman tumour is-


Options:
(1) [ans] well differentiated verrucous carcinoma (Score = 4.0)
(2) [  ] laryngeal tumour
(3) [  ] poorly differentiated colorectal carcinoma
(4) [  ] sternberg tumour

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Question ID: 14
Best contraceptive for patients of sickle cell anemia-


Options:
(1) [  ] OCP
(2) [  ] POP pills
(3) [  ] condoms
(4) [ans] DMPA (Score = 4.0)

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Question ID: 15
Which of the following is an antiapoptotic gene?


Options:
(1) [  ] c myc
(2) [  ] p 53
(3) [ans] bcl 2 (Score = 4.0)
(4) [  ] bax

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Question ID: 16
THE following are the complications aeen in "TETRALOGY OF
FALLOT"EXCEPT-



Options:
(1) [  ] hypercyanotic spells
(2) [  ] cerebral thrombosis
(3) [ans] congestive heart failure (Score = 4.0)
(4) [  ] congestive heart failure

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Question ID: 17
The Vitamin which has inhibitory effect on wound healing is



Options:
(1) [  ] Vitamin-A
(2) [ans] Vitamin-E (Score = 4.0)
(3) [  ] Vitamin-C
(4) [  ] Vitamin B-complex

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Question ID: 18
In a sutured surgical wound, the process of epithelialization is completed within



Options:
(1) [  ] 24 hrs
(2) [ans] 48 hrs (Score = 4.0)
(3) [  ] 72 hrs
(4) [  ] 96 hrs

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Question ID: 19
All of the following are X -linked disorder except-


Options:
(1) [  ] Emery - Dreifuss dystrophy
(2) [  ] Becker dystrophy
(3) [  ] Duchenne dystrophy
(4) [ans] Myotonic dystrophy (Score = 4.0)

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Question ID: 20
Plasma ferritin level may be reduced in all the following conditions except?


Options:
(1) [  ] Iron deficiency
(2) [  ] Vitamin C deficiency
(3) [ans] Liver disease (Score = 4.0)
(4) [  ] Hypothyroidism